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It was found that naltrexone and bupropion combined, which might be marketed down the road as Contrave, provide better weight loss results than eating and working out alone. Using two separate drugs to lose weight naturally can be very effective you can find combinations before the FDA now awaiting approval. When dealing with weight reduction and the people who go through it you ought to err to the side of caution and allow FDA do its job and demand some study be done so that the public is aware of the side effects and dangers of the medications before we drive them. Keep in mind that drug companies are in business to generate money and that they would say anything to keep people on their own medications. Researchers discovered that participants using this drug for a year, lost weight within four weeks and have kept the extra weight off throughout the 56 weeks in the study. Contrave is often a combination from the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs that are made up of multiple active ingredient, which might make them more potent and safer. Combo-pilling could be the newest fad or better yet the newest into the future under scrutiny and for that reason it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that using a combination of pills is becoming popular will be the fact that at the time of right now there are not any long term prescription slimming capsules that have been licensed by the FDA besides orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be authorized by the FDA. Seizures are a side effect with Contrave and shouldn't be taken in individuals with seizure disorders. The drug also can raise blood pressure and heart rate, and really should not be used in individuals with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure level and heart rate and must not be used in patients with uncontrolled high blood pressure level, along with by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients using a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes which has a boxed warning to alert medical professionals and patients towards the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking. New UCLA study on smokers with mental, drug, and alcohol problems